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Following decarboxylation from pyruvate, CoA binds to the ensuing 2-carbon molecule in order to create acetyl-CoA. So it compound will then be included in the brand new Krebs period, in which the acetyl group is fully oxidised so you can Carbon dioxide, creating NADH and FADH2 in the process. The fresh transportation out of pyruvate to your mitochondria try facilitated from the an excellent specific transportation healthy protein located in the mitochondrial membrane layer.
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